protocols reviewed within 24 hours
no membership required
Board Certified Physicians

Skin & Longevity

NAD+

NAD+ is a coenzyme every cell in the body needs to convert food into usable energy. As levels decline with age, NAD+ protocols are used to support the systems most affected — cellular energy, mental clarity, recovery, and the biological processes tied to healthy aging.

Physician-Supervised
Licensed US Compounding Pharmacy
Third-Party Tested
Prescription-Only

Injection method

$224/month

Select a plan

Start your protocol

Charged only after your protocol is approved. Cancel anytime.

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every cell — central to how the body produces energy, repairs DNA, and manages cellular stress. Unlike a vitamin, it's not something you can store or supplement in usable form; the body produces it continuously, and production slows with age.

Injected NAD+ replenishes the molecule directly, supporting the pathways that depend on it most — the ones that show the strain first as levels fall.

NAD+ is administered as a subcutaneous injection, usually in the morning — the timing that aligns with its energizing effect. Your clinician sets the dose and cycle length at intake, and some protocols start lower and titrate up over the first weeks.

Everything you need to inject at home, in one shipment:

The vial, lyophilized and ready to reconstitute
Bacteriostatic water for reconstitution
Insulin syringes
Alcohol prep pads
Step-by-step reconstitution and injection instructions in your care portal
Sharps disposal guidance

Every prescription is written by a US-licensed clinician after reviewing your intake. It's compounded at a licensed US 503A pharmacy held to cGMP manufacturing standards, and every batch is third-party tested for potency, sterility, pH balance, and endotoxins before it ships. Temperature-controlled from the pharmacy to your door. Full results in the Quality panel below.

Why NAD+

Restores Energy

Replenishes cellular energy production and reduces fatigue.

Sharpens Focus

Sharper mental clarity and steadier focus through the day.

Recovery & Repair

Faster physical recovery and sharper resilience under sustained load.

Supports Healthy Aging

Reinforces DNA repair and cellular regeneration - central pathways for long-term resilience.

Restores Energy

Replenishes cellular energy production and reduces fatigue.

Sharpens Focus

Sharper mental clarity and steadier focus through the day.

Recovery & Repair

Faster physical recovery and sharper resilience under sustained load.

Supports Healthy Aging

Reinforces DNA repair and cellular regeneration - central pathways for long-term resilience.

Restores Energy

Replenishes cellular energy production and reduces fatigue.

Sharpens Focus

Sharper mental clarity and steadier focus through the day.

Recovery & Repair

Faster physical recovery and sharper resilience under sustained load.

Supports Healthy Aging

Reinforces DNA repair and cellular regeneration - central pathways for long-term resilience.

Restores Energy

Replenishes cellular energy production and reduces fatigue.

Sharpens Focus

Sharper mental clarity and steadier focus through the day.

Recovery & Repair

Faster physical recovery and sharper resilience under sustained load.

Supports Healthy Aging

Reinforces DNA repair and cellular regeneration - central pathways for long-term resilience.

How it works

The path to your protocol.

From your intake to your door, every protocol is built by a licensed US clinician around who you are and where you're headed.

Take the assessment.

[01]

Your goals, your body, your history - everything your clinician needs to build a protocol around you.

Clinician-built protocol.

[02]

A US-licensed clinician reviews your intake, selects the right compound, dose and cycle, and approves your protocol within 24 hours.

Delivered. Then evolved.

[03]

Compounded at a licensed US pharmacy and shipped discreetly. Monthly check-ins keep your clinician close and your protocol evolving with you.

Start your protocol

Tested every batch. Independently.

Every SYNC protocol is compounded at a licensed US 503A pharmacy and third-party tested — every batch, against four pharmacopoeia standards. If a batch doesn't pass all four, it doesn't ship.

Potency

Passed

Confirms the vial contains what the label says — active ingredient within ±10% of prescribed concentration.

Sterility

Passed

Tested against USP 797 to confirm the compound is free from bacterial or fungal contamination.

pH balance

Passed

Balanced to minimise irritation at the injection site and remain compatible with the body.

Endotoxins

Passed

Tested against USP 85 to confirm bacterial endotoxin levels are within safe limits — protecting against fever and adverse reactions.

FROM THE COMMUNITY

The ones who stopped guessing

Excellent

"I've never had healthcare feel this frictionless. From the intake to messaging my clinician, everything just works - I ask a question, I get a real answer, and my protocol keeps moving. It's the kind of experience I wish more of healthcare felt like."

Jackson P.Metabolic protocol

"My cycle 2 protocol was genuinely different from cycle 1- the dose had been adjusted and one of the compounds swapped based on how I'd responded. It's the first time I've seen personalization actually happen, not just be marketed."

Chase H.Longevity protocol

"I'd done my research on peptides - the question wasn't whether to take them, it was who to trust. SYNC was the first place where the intake felt like actual medicine. My physician walked me through her reasoning before prescribing anything."

Nicki K.verified member

Jackson P.Metabolic protocol

Chase H.Longevity protocol

Nicki K.verified member

Jackson P.Metabolic protocol

Chase H.Longevity protocol

Nicki K.verified member

Jackson P.Metabolic protocol

Chase H.Longevity protocol

Nicki K.verified member

The catalog

The architecture of in sync.

Metabolic

Compounded Tirzepatide

Dual-action weight management, once weekly.

Start your protocol

Metabolic

Compounded Semaglutide

Appetite, weight and metabolic support.

Start your protocol

LONGEVITY

NAD+

Cellular energy and repair support.

START YOUR PROTOCOL

METABOLIC

Tesamorelin

Visceral fat and body composition support.

START YOUR PROTOCOL

HORMONAL

PT-141

Supports desire and arousal response.

START YOUR PROTOCOL

PERFORMANCE

Sermorelin

Recovery, sleep and body composition support.

start your protocol

Shop all

Learn

The SYNC journal.

Physician-informed articles on the compounds, protocols and the research behind them.

SCIENCE

How to get peptides prescribed online: a step-by-step guide.

How to Get Peptides Prescribed Online (2026 Guide)

SAFETY

Are peptides safe? What to know before you start.

Are Peptides Safe? What to Know Before You Start (2026)

HORMONAL

PT-141 (bremelanotide): how it works for men and women.

PT-141 (Bremelanotide): How It Works for Men and Women

View all articles

FAQ

Everything worth asking.

Protocols, prescriptions, and what happens after you order.

Contact our care team

NAD+ isn't a nutrient you're missing or a hormone you're deficient in — it's the coenzyme every cell uses to produce energy, repair DNA, and manage stress. Levels naturally decline with age, which is why the systems that depend most on it — energy, cognition, recovery — are usually the first to show the strain. Replenishing NAD+ directly supports the pathways where that decline is felt.

IV NAD+ delivers a single high dose in one clinic session — useful for acute one-off dosing, less practical for the sustained support NAD+ protocols are built for. Subcutaneous delivers steady dosing over a full cycle, which is how the body actually uses NAD+ — replenished consistently, not spiked once. For most goals, subq is the protocol shape that matches the mechanism.

NAD+ supports mitochondrial energy production and cellular repair — the systems athletes depend on for training capacity and recovery. Reported effects include faster recovery between sessions, sharper focus during training, and better resilience under sustained load. Clinical data on direct performance metrics is still developing; the mechanism is what athletes are targeting.

The mechanism is clear: NAD+ declines with age, and the systems that depend on it — cellular energy, DNA repair, metabolic regulation — decline alongside it. Restoring NAD+ supports those systems at the level they depend on. Whether that translates to measurably slower biological aging is still an active research question. What's clearer is the felt experience of aging — energy, cognition, recovery — is where NAD+ supplementation most reliably shows up.

Energy and mental clarity changes are often felt within 2-4 weeks of consistent dosing. Recovery, sleep, and resilience changes usually build over 8-12 weeks. Individual response varies — some people notice sharp improvements early, others feel gradual shifts. Your clinician tracks response at check-in and adjusts the protocol accordingly.

NAD+ stacks cleanly with most SYNC protocols — PERFORM, REPAIR, and RESTORE all run on separate pathways and layer without interaction. Certain medications need clinical review before starting. Tell us everything you're taking at intake — your clinician reviews the full picture before prescribing.

Reach out through your care portal — your clinician can review your protocol and expedite a refill if needed. Most reorders ship within 1-2 business days once approved.

Any time, from your account. If your goals change, message us and we'll adjust your protocol with you. No calls, no retention scripts, no penalty for pausing between cycles.

No insurance — SYNC is cash-pay, which lets us build every protocol around your body rather than around what an insurer will approve. HSA and FSA cards work at checkout like any credit or debit card. Reimbursement depends on your individual plan — if you're unsure, check with your provider or ask your clinician for a Letter of Medical Necessity.

Yes. Buy Now, Pay Later is available on 3-month subscriptions or longer, selectable at checkout. One-time orders and shorter subscriptions are paid upfront.

Your protocol, your body

Stop guessing. Start your protocol.

Five-minute assessment. A licensed clinician builds it. No charge until your protocol is approved.

Start your protocol

Why NAD+

Restores Energy

Replenishes cellular energy production and reduces fatigue.

Sharpens Focus

Sharper mental clarity and steadier focus through the day.

Recovery & Repair

Faster physical recovery and sharper resilience under sustained load.

Supports Healthy Aging

Reinforces DNA repair and cellular regeneration - central pathways for long-term resilience.

Restores Energy

Replenishes cellular energy production and reduces fatigue.

Sharpens Focus

Sharper mental clarity and steadier focus through the day.

Recovery & Repair

Faster physical recovery and sharper resilience under sustained load.

Supports Healthy Aging

Reinforces DNA repair and cellular regeneration - central pathways for long-term resilience.

Restores Energy

Replenishes cellular energy production and reduces fatigue.

Sharpens Focus

Sharper mental clarity and steadier focus through the day.

Recovery & Repair

Faster physical recovery and sharper resilience under sustained load.

Supports Healthy Aging

Reinforces DNA repair and cellular regeneration - central pathways for long-term resilience.

Restores Energy

Replenishes cellular energy production and reduces fatigue.

Sharpens Focus

Sharper mental clarity and steadier focus through the day.

Recovery & Repair

Faster physical recovery and sharper resilience under sustained load.

Supports Healthy Aging

Reinforces DNA repair and cellular regeneration - central pathways for long-term resilience.