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Sermorelin

Sermorelin is a peptide modelled on GHRH, the brain's signal to release growth hormone, prompting the body to produce its own rather than replacing it. In protocol, it's used to support what changes as GH output declines through midlife: sleep quality, training recovery, and body composition.

Physician-Supervised
Licensed US Compounding Pharmacy
Third-Party Tested
Prescription-Only

Injection method

$206/month

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Charged only after your protocol is approved. Cancel anytime.

Sermorelin is a synthetic version of GHRH (growth hormone releasing hormone), the signal the brain sends to the pituitary to prompt GH release. Rather than adding hormone from outside, it works upstream: signalling the body to produce its own, in the natural pulsatile rhythm the endocrine system is built for. Because the body stays in control of how much it releases and when, the response works with the endocrine system rather than around it.

Sermorelin is administered as a subcutaneous injection before bed — timing that aligns with the body's natural overnight GH release. Your clinician sets your exact dose, cycle length, and any titration schedule based on your intake.

How the protocol runs from there depends on the goal. Some cycles run continuously across several months; others use scheduled breaks to keep the pituitary responsive over the long term. That's a decision your clinician makes with you at intake and revisits at each check-in.

Everything you need to inject at home, in one shipment:

The vial, lyophilized and ready to reconstitute
Bacteriostatic water for reconstitution
Insulin syringes
Alcohol prep pads
Step-by-step reconstitution and injection instructions in your care portal
Sharps disposal guidance

Every prescription is written by a US-licensed clinician after reviewing your intake. It's compounded at a licensed US 503A pharmacy held to cGMP manufacturing standards, and every batch is third-party tested for potency, sterility, pH balance, and endotoxins before it ships. Temperature-controlled from the pharmacy to your door. Full results in the Quality panel below.

Why Sermorelin

Improves Sleep Quality

Supports the slow-wave sleep stages where the body does most of its overnight repair.

Speeds Recovery

Contributes to the body's repair processes between sessions and after harder training loads.

Leaner Composition

Supports lean body composition and healthy body weight.

Restores Energy

Better sleep and recovery flow into how the day runs — energy, focus, drive.

Improves Sleep Quality

Supports the slow-wave sleep stages where the body does most of its overnight repair.

Speeds Recovery

Contributes to the body's repair processes between sessions and after harder training loads.

Leaner Composition

Supports lean body composition and healthy body weight.

Restores Energy

Better sleep and recovery flow into how the day runs — energy, focus, drive.

Improves Sleep Quality

Supports the slow-wave sleep stages where the body does most of its overnight repair.

Speeds Recovery

Contributes to the body's repair processes between sessions and after harder training loads.

Leaner Composition

Supports lean body composition and healthy body weight.

Restores Energy

Better sleep and recovery flow into how the day runs — energy, focus, drive.

Improves Sleep Quality

Supports the slow-wave sleep stages where the body does most of its overnight repair.

Speeds Recovery

Contributes to the body's repair processes between sessions and after harder training loads.

Leaner Composition

Supports lean body composition and healthy body weight.

Restores Energy

Better sleep and recovery flow into how the day runs — energy, focus, drive.

How it works

The path to your protocol.

From your intake to your door, every protocol is built by a licensed US clinician around who you are and where you're headed.

Take the assessment.

[01]

Your goals, your body, your history - everything your clinician needs to build a protocol around you.

Clinician-built protocol.

[02]

A US-licensed clinician reviews your intake, selects the right compound, dose and cycle, and approves your protocol within 24 hours.

Delivered. Then evolved.

[03]

Compounded at a licensed US pharmacy and shipped discreetly. Monthly check-ins keep your clinician close and your protocol evolving with you.

Start your protocol

Tested every batch. Independently.

Every SYNC protocol is compounded at a licensed US 503A/503B pharmacy and third-party tested — every batch, against four pharmacopoeia standards. If a batch doesn't pass all four, it doesn't ship.

Potency

Passed

Confirms the vial contains what the label says — active ingredient within ±10% of prescribed concentration.

Sterility

Passed

Tested against USP 797 to confirm the compound is free from bacterial or fungal contamination.

pH balance

Passed

Balanced to minimise irritation at the injection site and remain compatible with the body.

Endotoxins

Passed

Tested against USP 85 to confirm bacterial endotoxin levels are within safe limits — protecting against fever and adverse reactions.

FROM THE COMMUNITY

The ones who stopped guessing

Excellent

"I've never had healthcare feel this frictionless. From the intake to messaging my clinician, everything just works - I ask a question, I get a real answer, and my protocol keeps moving. It's the kind of experience I wish more of healthcare felt like."

Jackson P.Metabolic protocol

"My cycle 2 protocol was genuinely different from cycle 1- the dose had been adjusted and one of the compounds swapped based on how I'd responded. It's the first time I've seen personalization actually happen, not just be marketed."

Chase H.Longevity protocol

"I'd done my research on peptides - the question wasn't whether to take them, it was who to trust. SYNC was the first place where the intake felt like actual medicine. My physician walked me through her reasoning before prescribing anything."

Nicki K.verified member

Jackson P.Metabolic protocol

Chase H.Longevity protocol

Nicki K.verified member

Jackson P.Metabolic protocol

Chase H.Longevity protocol

Nicki K.verified member

Jackson P.Metabolic protocol

Chase H.Longevity protocol

Nicki K.verified member

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The SYNC journal.

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FAQ

Everything worth asking.

Protocols, prescriptions, and what happens after you order.

Contact our care team

HGH is a direct injection of synthetic growth hormone into the body. Sermorelin doesn't add hormone — it signals your pituitary to release its own, in the natural pulsatile rhythm your endocrine system is built for. That means the response is gradual rather than dramatic, and the body retains its own feedback control over how much GH it releases.

Sermorelin is typically prescribed for adults noticing the sleep, recovery, and body composition shifts that come with declining GH output — usually from the mid-30s onward, in men and women. It's commonly run alongside other hormone therapies, peptide protocols, or ongoing medication.

Most people tolerate Sermorelin well. The most common reactions are transient — mild redness or swelling at the injection site, occasional flushing, or a warm sensation that passes within an hour. Some people notice mild water retention or tingling in the hands during the first weeks, which typically settles as your body adjusts.

Anything concerning while on protocol — you message us and we adjust.

Sermorelin works gradually — it's stimulating your body's own GH production, so the response builds over cycles rather than in the first week. Most people notice sleep quality changes in the first month. Recovery and body composition changes tend to land in months two and three.

Any time, from your account. If your goals change, message us and we'll adjust your protocol with you. No calls, no retention scripts, no penalty for pausing between cycles.

Message us and we'll expedite a replacement — most reorders ship the same day. Your subscription is timed so this shouldn't happen, but if life gets in the way, we've got you.

No insurance — SYNC is cash-pay, which lets us build every protocol around your body rather than around what an insurer will approve. HSA and FSA cards work at checkout like any credit or debit card. Reimbursement depends on your individual plan — if you're unsure, check with your provider or ask your clinician for a Letter of Medical Necessity.

Yes. Buy Now, Pay Later is available on 3-month subscriptions or longer, selectable at checkout. One-time orders and shorter subscriptions are paid upfront.

Your protocol, your body

Stop guessing. Start your protocol.

Five-minute assessment. A licensed clinician builds it. No charge until your protocol is approved.

Start your protocol

Why Sermorelin

Improves Sleep Quality

Supports the slow-wave sleep stages where the body does most of its overnight repair.

Speeds Recovery

Contributes to the body's repair processes between sessions and after harder training loads.

Leaner Composition

Supports lean body composition and healthy body weight.

Restores Energy

Better sleep and recovery flow into how the day runs — energy, focus, drive.

Improves Sleep Quality

Supports the slow-wave sleep stages where the body does most of its overnight repair.

Speeds Recovery

Contributes to the body's repair processes between sessions and after harder training loads.

Leaner Composition

Supports lean body composition and healthy body weight.

Restores Energy

Better sleep and recovery flow into how the day runs — energy, focus, drive.

Improves Sleep Quality

Supports the slow-wave sleep stages where the body does most of its overnight repair.

Speeds Recovery

Contributes to the body's repair processes between sessions and after harder training loads.

Leaner Composition

Supports lean body composition and healthy body weight.

Restores Energy

Better sleep and recovery flow into how the day runs — energy, focus, drive.

Improves Sleep Quality

Supports the slow-wave sleep stages where the body does most of its overnight repair.

Speeds Recovery

Contributes to the body's repair processes between sessions and after harder training loads.

Leaner Composition

Supports lean body composition and healthy body weight.

Restores Energy

Better sleep and recovery flow into how the day runs — energy, focus, drive.