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Recovery

TB-500

TB-500 is a peptide that drives the body's cellular repair response — supporting recovery in muscle, tendon, ligament, and connective tissue after injury, training load, or long-term wear.

It works systemically, moving through the bloodstream to areas of active repair rather than targeting one site, making it the foundation for whole-body tissue recovery and long-term resilience.

Prescribed by board-certified US doctors & clinicians
Active ingredients from FDA-registered facilities
Prescriptions filled by licensed US pharmacies
Guided by your clinician at every step

Injection method

$206/month

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Charged only after your protocol is approved. Cancel anytime.

TB-500 is a peptide based on a naturally occurring protein the body uses to signal repair after injury. Its role is to move cells to damaged tissue, form new blood vessels, and rebuild the structural fibres that carry load — the same three processes that determine how fast the body heals and how well the tissue holds up afterward.

As natural levels of this repair signal decline with age, training load, and cumulative wear, healing slows, injuries linger, and connective tissue loses resilience. TB-500 restores that signal at a level the body can act on, driving the repair response across muscle, tendon, ligament, and fascia rather than one site at a time.

TB-500 is administered as a subcutaneous injection, typically twice per week during a loading phase, then adjusted to a maintenance dose that sustains long-term tissue resilience.

Protocols run in structured cycles — commonly eight to twelve weeks for acute recovery, with many patients continuing into six-month arcs to compound repair across multiple areas and build the connective tissue capacity that carries long-term training and daily load. Your clinician sets dose, frequency, and cycle length at intake based on your recovery goal, injury history, and how you plan to use the resilience once it's built.

Everything you need to inject at home, in one shipment:

The vial, lyophilized and ready to reconstitute
Bacteriostatic water for reconstitution
Insulin syringes
Alcohol prep pads
Step-by-step reconstitution and injection instructions in your care portal
Sharps disposal guidance

Every prescription is written by a US-licensed clinician after reviewing your intake. It's compounded at a licensed US 503A pharmacy held to cGMP manufacturing standards, and every batch is third-party tested for potency, sterility, pH balance, and endotoxins before it ships. Temperature-controlled from the pharmacy to your door. Full results in the Quality panel below.

Important Safety Information

Why TB-500

Accelerates Tissue Repair

Drives the cell migration and regeneration that carry muscle, tendon, and ligament recovery.

Restores Connective Tissue

Supports repair of the tissue that carries load, from tendons to fascia to joints.

Reduces Recovery Downtime

Compounds the body's natural repair timeline to restore full function sooner.

Regulates Inflammation

Steadies the inflammatory response, supporting healing without suppressing it.

Accelerates Tissue Repair

Drives the cell migration and regeneration that carry muscle, tendon, and ligament recovery.

Restores Connective Tissue

Supports repair of the tissue that carries load, from tendons to fascia to joints.

Reduces Recovery Downtime

Compounds the body's natural repair timeline to restore full function sooner.

Regulates Inflammation

Steadies the inflammatory response, supporting healing without suppressing it.

Accelerates Tissue Repair

Drives the cell migration and regeneration that carry muscle, tendon, and ligament recovery.

Restores Connective Tissue

Supports repair of the tissue that carries load, from tendons to fascia to joints.

Reduces Recovery Downtime

Compounds the body's natural repair timeline to restore full function sooner.

Regulates Inflammation

Steadies the inflammatory response, supporting healing without suppressing it.

Accelerates Tissue Repair

Drives the cell migration and regeneration that carry muscle, tendon, and ligament recovery.

Restores Connective Tissue

Supports repair of the tissue that carries load, from tendons to fascia to joints.

Reduces Recovery Downtime

Compounds the body's natural repair timeline to restore full function sooner.

Regulates Inflammation

Steadies the inflammatory response, supporting healing without suppressing it.

How it works

The path to your protocol.

From your intake to your door, every protocol is built by a licensed US clinician around who you are and where you're headed.

Take the assessment.

[01]

Your goals, your body, your history - everything your clinician needs to build a protocol around you.

Clinician-built protocol.

[02]

A US-licensed clinician reviews your intake, selects the right compound, dose and cycle, and approves your protocol within 24 hours.

Delivered. Then evolved.

[03]

Compounded at a licensed US pharmacy and shipped discreetly. Monthly check-ins keep your clinician close and your protocol evolving with you.

Start your protocol

Tested every batch. Independently.

Every SYNC protocol is compounded at a licensed US 503A pharmacy and third-party tested — every batch, against four pharmacopoeia standards. If a batch doesn't pass all four, it doesn't ship.

Potency

Passed

Confirms the vial contains what the label says — active ingredient within ±10% of prescribed concentration.

Sterility

Passed

Tested against USP 797 to confirm the compound is free from bacterial or fungal contamination.

pH balance

Passed

Balanced to minimise irritation at the injection site and remain compatible with the body.

Endotoxins

Passed

Tested against USP 85 to confirm bacterial endotoxin levels are within safe limits — protecting against fever and adverse reactions.

FROM THE COMMUNITY

The ones who stopped guessing

Excellent4

"I've never had healthcare feel this frictionless. From the intake to messaging my clinician, everything just works - I ask a question, I get a real answer, and my protocol keeps moving. It's the kind of experience I wish more of healthcare felt like."

Jackson P.4Metabolic protocol

"My cycle 2 protocol was genuinely different from cycle 1- the dose had been adjusted and one of the compounds swapped based on how I'd responded. It's the first time I've seen personalization actually happen, not just be marketed."

Chase H.Longevity protocol

"I'd done my research on peptides - the question wasn't whether to take them, it was who to trust. SYNC was the first place where the intake felt like actual medicine. My physician walked me through her reasoning before prescribing anything."

Nicki K.verified member

Jackson P.4Metabolic protocol

Chase H.Longevity protocol

Nicki K.verified member

Jackson P.4Metabolic protocol

Chase H.Longevity protocol

Nicki K.verified member

Jackson P.4Metabolic protocol

Chase H.Longevity protocol

Nicki K.verified member

The catalog

The architecture of in sync.

Metabolic

Compounded Tirzepatide

Dual-action weight management, once weekly.

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Metabolic

Compounded Semaglutide

Appetite, weight and metabolic support.

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METABOLIC

MOTS-C

Mitochondrial and metabolic health support.

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METABOLIC

Tesamorelin

Visceral fat and body composition support.

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RECOVERY

BPC-157

Tissue and gut repair support.

start your protocol

RECOVERY

TB-500

Muscle, tendon and ligament recovery support.

Start Your Protocol

LONGEVITY

NAD+

Cellular energy and repair support.

Start Your Protocol

PERFORMANCE

Sermorelin

Recovery, sleep and body composition support.

Start Your Protocol

HORMONAL

PT-141

Supports desire and arousal response.

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Shop all

Learn

The SYNC journal.

Physician-informed articles on the compounds, protocols and the research behind them.

SCIENCE

How to get peptides prescribed online: a step-by-step guide.

How to Get Peptides Prescribed Online (2026 Guide)

SAFETY

Are peptides safe? What to know before you start.

Are Peptides Safe? What to Know Before You Start (2026)

HORMONAL

PT-141 (bremelanotide): how it works for men and women.

PT-141 (Bremelanotide): How It Works for Men and Women

View all articles

FAQ

Everything worth asking.

Protocols, prescriptions, and what happens after you order.

Contact our care team

Both are recovery peptides but they do different jobs. BPC-157 works primarily on the gut, vascular system, and localised inflammation — the healing signal for that region. TB-500 works systemically on tissue repair — driving cell migration and regeneration across muscle, tendon, ligament, and connective tissue. Many patients run them together in a sequenced protocol for compounded recovery.

Adults working on injury recovery, soft tissue repair, or long-term training resilience. TB-500 pairs well with BPC-157, GHK-Cu, DSIP, and other recovery protocols across the SYNC catalogue — the TB-500/BPC-157 combination especially is one of the most established pairings for structured recovery. It's not appropriate during active cancer treatment. Share your injury history, training load, and current protocols at intake and your clinician builds the protocol around it.

No. TB-500 works systemically once in the bloodstream — the peptide migrates to areas of active tissue repair on its own. Subcutaneous injection at the standard rotation sites delivers the systemic dose, which is why site management is straightforward and clinician-directed.

Most patients notice reduced soreness and improved recovery pace within the first two to three weeks. Soft tissue and connective tissue repair typically shifts across the eight to twelve week cycle, with continued gains for patients who extend into six-month arcs to compound the repair.

TB-500 works with the body's own repair signaling — no dependence, no downregulation. Tissue gains built during a cycle hold longest for patients who continue with structured strength and mobility work between cycles, which is why many return for follow-on protocols as part of an ongoing recovery rhythm.

Message us and we'll expedite a replacement — most reorders ship the same day. Your subscription is timed so this shouldn't happen, but if life gets in the way, we've got you.

Any time, from your account. If your goals change, message us and we'll adjust your protocol with you. No calls, no retention scripts, no penalty for pausing between cycles.

No insurance — SYNC is cash-pay, which lets us build every protocol around your body rather than around what an insurer will approve. HSA and FSA cards work at checkout like any credit or debit card. Reimbursement depends on your individual plan — if you're unsure, check with your provider or ask your clinician for a Letter of Medical Necessity.

Yes. Buy Now, Pay Later is available on 3-month subscriptions or longer, selectable at checkout. One-time orders and shorter subscriptions are paid upfront.

Your protocol, your body

Stop guessing. Start your protocol.

Five-minute assessment. A licensed clinician builds it. No charge until your protocol is approved.

Start your protocol

Why TB-500

Accelerates Tissue Repair

Drives the cell migration and regeneration that carry muscle, tendon, and ligament recovery.

Restores Connective Tissue

Supports repair of the tissue that carries load, from tendons to fascia to joints.

Reduces Recovery Downtime

Compounds the body's natural repair timeline to restore full function sooner.

Regulates Inflammation

Steadies the inflammatory response, supporting healing without suppressing it.

Accelerates Tissue Repair

Drives the cell migration and regeneration that carry muscle, tendon, and ligament recovery.

Restores Connective Tissue

Supports repair of the tissue that carries load, from tendons to fascia to joints.

Reduces Recovery Downtime

Compounds the body's natural repair timeline to restore full function sooner.

Regulates Inflammation

Steadies the inflammatory response, supporting healing without suppressing it.

Accelerates Tissue Repair

Drives the cell migration and regeneration that carry muscle, tendon, and ligament recovery.

Restores Connective Tissue

Supports repair of the tissue that carries load, from tendons to fascia to joints.

Reduces Recovery Downtime

Compounds the body's natural repair timeline to restore full function sooner.

Regulates Inflammation

Steadies the inflammatory response, supporting healing without suppressing it.

Accelerates Tissue Repair

Drives the cell migration and regeneration that carry muscle, tendon, and ligament recovery.

Restores Connective Tissue

Supports repair of the tissue that carries load, from tendons to fascia to joints.

Reduces Recovery Downtime

Compounds the body's natural repair timeline to restore full function sooner.

Regulates Inflammation

Steadies the inflammatory response, supporting healing without suppressing it.